PUBLICATIONS

2024

Hakobyan A, Meyenberg M, Vardazaryan N, Hancock J, Vulliard L, Loizou JI, et al. Pan-cancer analysis of the interplay between mutational signatures and cellular signaling. iScience. 2024;27:109873.
Hakobyan M, Binder H, Arakelyan A. Pan-canceranalysis of telomere maintenance mechanisms. Journal of Biological Chemistry.2024;300.
Schmidt M․, Avagyan S․, Reiche K., Binder B., Loeffler-Wirth H. (2024). A Spatial Transcriptomics Browser for Discovering Gene Expression Landscapes across Microscopic Tissue Sections. Current Issues in Molecular Biology. 2024, 46(5), 4701-4720.
Arakelyan A, Avagyan S, Kurnosov A, Mkrtchyan T, Mkrtchyan G, Zakharyan R, R Mayilyan K, Binder H. Temporal changes of gene expression in health, schizophrenia, bipolar disorder, and major depressive disorder. Schizophrenia. 2024;10.
Martirosyan A, Ansari R, Pestana F, Hebestreit K, Gasparyan H, Aleksanyan R, et al. Unravelling cell type-specific responses to Parkinson’s Disease at single cell resolution. Molecular Neurodegeneration 2024 19:1. 2024;19:1–24.

2023

Everest-Dass A, Nersisyan S, Maar H, Novosad V, Schröder-Schwarz J, Freytag V, et al. Spontaneous metastasis xenograft models link CD44 isoform 4 to angiogenesis, hypoxia, EMT and mitochondria-related pathways in colorectal cancer. Mol Oncol. 2024;18.
Hakobyan S, Stepanyan A, Nersisyan L, Binder H, Arakelyan A. PSF toolkit: an R package for pathway curation and topology-aware analysis. Front Genet. 2023;14:1264656.
Ashekyan O, Shahbazyan N, Bareghamyan Y, Kudryavzeva A, Mandel D, Schmidt M,...Binder H. Transcriptomic Maps of Colorectal Liver Metastasis: Machine Learning of Gene Activation Patterns and Epigenetic Trajectories in Support of Precision Medicine. Cancers 2023, Vol 15, Page 3835. 2023;15:3835.
Avagyan S, Binder H. Subtyping or not subtyping—Quo vadis for precision medicine of colorectal cancer. Transl Cancer Res. 2023;12:1067–72.
Huch S, Nersisyan L, Ropat M, Barrett D, Wu M, Wang J, et al. Atlas of mRNA translation and decay for bacteria. Nature Microbiology 2023 8:6. 2023;8:1123–36.
Zhiyanov A, Engibaryan N, Nersisyan S, Shkurnikov M, Tonevitsky A. Differential co-expression network analysis with DCoNA reveals isomiR targeting aberrations in prostate cancer. Bioinformatics. 2023. https://doi.org/10.1093/BIOINFORMATICS/BTAD051.
Shkurnikov M, Nersisyan S, Averinskaya D, Chekova M, Polyakov F, Titov A, et al. HLA-A*01:01 allele diminishing in COVID-19 patients population associated with non-structural epitope abundance in CD8+ T-cell repertoire. PeerJ. 2023;11:e14707.

2022

Nersisyan S, Gorbonos A, Makhonin A, Zhiyanov A, Shkurnikov M, Tonevitsky A. isomiRTar: a comprehensive portal of pan-cancer 50-isomiR targeting. PeerJ. 2022;10:e14205.
Loeffler-Wirth H, Rade M, Arakelyan A, Kreuz M, Loeffler M, Koehl U, Reiche K, Binder H. Transcriptional states of CAR-T infusion relate to neurotoxicity – lessons from high-resolution single-cell SOM expression portraying. Front Immunol. 2022;13:5395.
Binder H, Schmidt M, Hopp L, Davitavyan S, Arakelyan A, Loeffler-Wirth H. Integrated Multi-Omics Maps of Lower-Grade Gliomas. Cancers 2022, Vol 14, Page 2797. 2022;14:2797.
Nersisyan S, Zhiyanov A, Zakharova M, Ishina I, Kurbatskaia I, Mamedov A, et al. Alterations in SARS-CoV-2 Omicron and Delta peptides presentation by HLA molecules. PeerJ. 2022;10:e13354.
Nikoghosyan M, Loeffler-Wirth H, Davidavyan S, Binder H, Arakelyan A. Projection of High-Dimensional Genome-Wide Expression on SOM Transcriptome Landscapes. BioMedInformatics 2022, Vol 2, Pages 62-76. 2022;2:62–76.
Loeffler-Wirth H, Hopp L, Schmidt M, Zakharyan R, Arakelyan A, Binder H. The Transcriptome and Methylome of the Developing and Aging Brain and Their Relations to Gliomas and Psychological Disorders. Cells 2022, Vol 11, Page 362. 2022;11:362.
Goukassian D, Arakelyan A, Brojakowska A, Bisserier M, Hakobyan S, Hadri L, et al. Space flight associated changes in astronauts’ plasma-derived small extracellular vesicle microRNA: Biomarker identification. Clin Transl Med. 2022;12:e845.

2021

Schmidt M, Arshad M, Bernhart SH, Hakobyan S, Arakelyan A, Loeffler-Wirth H, Binder H. The Evolving Faces of the SARS-CoV-2 Genome. Viruses 2021, Vol 13, Page 1764. 2021;13:1764.
Willscher E, Hopp L, Kreuz M, Schmidt M, Hakobyan S, Arakelyan A... Binder H. High-Resolution Cartography of the Transcriptome and Methylome Landscapes of Diffuse Gliomas. Cancers 2021, Vol 13, Page 3198. 2021;13:3198.
Al-Sanea MM, Chilingaryan G, Abelyan N, Sargsyan A, Hovhannisyan S, Gasparyan H, et al. Identification of Novel Potential VEGFR-2 Inhibitors Using a Combination of Computational Methods for Drug Discovery. Life 2021, Vol 11, Page 1070. 2021;11:1070.