Siras Hakobayan is a Bioinformatics Ph.D. student in the Bioinformatics group at the Institute of Molecular Biology. He received his bachelor’s and master’s degrees in bioinformatics at Yerevan State University. He started his first bioinformatics project in the last year of his bachelor’s degree which was remotely supervised by Ogsen Gabrielyan. Afterwards, Siras joined the genome bioinformatics group at the Institute of Molecular biology in 2016. Since then, he has been working on different genome bioinformatics-related projects. He started his Ph.D. in 2019 which focuses on the pathway-centered analysis of high-throughput omics data. Particularly, analyzing pathway activity states in cancers based on pathway topology, gene expression, and somatic mutation data.
Siras Hakobyan was a mentor during the OMICS 2021 Summer School and now supervises ABI Student Mher Kurghinyan on his project about signaling pathways states in health and disease with integrative genomics.
Research Interests
- Cancer bioinformatics
- Pathway analysis
- NGS data analysis
Publications
Arakelyan, A., Nersisyan, L., Nikoghosyan, M., Hakobyan, S., Simonyan, A., Hopp, L., Loeffler-Wirth, H., & Binder, H. Transcriptome-guided drug repositioning. Pharmaceutics. 2019, 11(12), 677 doi: https://doi.org/10.3390/pharmaceutics11120677
Hakobyan S Loeffler-Wirth H Arakelyan A Binder H Kunz M A Transcriptome-Wide Isoform Landscape of Melanocytic Nevi and Primary Melanomas Identifies Gene Isoforms Associated with Malignancy International journal of molecular sciences 2021/1 22(13) 7165 doi: https://doi.org/10.3390/ijms22137165
Schmidt M Arshad M Bernhart H S Hakobyan S Arakelyan A Loeffler-Wirth H Binder H The evolving faces of the SARS-CoV-2 genome Viruses 2021/9 13(9) 1764 doi: https://doi.org/10.3390/v13091764