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Nersisyan Lab

The lab’s central interest is the development of algorithms and software solutions for genomics research. The team is currently focused on

  • microbiome research,
  • mRNA degradome analysis,
  • genetic engineering applications.

Team

Nelly Vardazaryan

MSc Student

Tatevik Jalatyan

BSc Student

Jakub Wudarski
Specially Appointed Assistant Professor at National Institute for Basic Biology Japan

Daria Laricheva

BSc Student

Valeri Vardanyan

Cosmologist and astrophysicist, Kavli fellow at IPMU

Relevant Publications

S Huch, L Nersisyan, M Ropat, D Barret, J Wang, J Huerta-Cepas, W Wei, L M Steinmetz, L Engstand, V Pelechano. RNA degradation analysis reveals ribosome dynamics in complex microbiome samples. medRxiv. 2021.04.08.439066.

L Nersisyan, M Ropat, V Pelechano. Improved computational analysis of ribosome dynamics from 5′P degradome data using fivepseq. NAR Genomics and Bioinformatics. 2020. Volume 2, Issue 4, lqaa099.

L Nersisyan, M Nikoghosyan, The Genome if the Netherlands consortium & A Arakelyan. WGS-based telomere length analysis in Dutch family trios implicates stronger maternal inheritance and a role for RRM1 gene. Scientific Reports. 2019. Volume 9, Article number: 18758.

L Nersisyan, L Hopp, H Loeffler-Wirth, J Galle, M Loeffler, A Arakelyan, H Binder. Telomere Length Maintenance and Its Transcriptional Regulation in Lynch Syndrome and Sporadic Colorectal Carcinoma. Frontiers in oncology. 2019. Volume 9.

L Nersisyan, G Johnson, M Riel-Mehan, A R Pico, A Arakelyan. PSFC: a Pathway Signal Flow Calculator App for Cytoscape. F1000Research. 2015. Version 2. 4: 480.

L Nersisyan, A Arakelyan. Computel: Computation of Mean Telomere Length from Whole-Genome Next-Generation Sequencing Data. PLoS one. 2015. Volume 10, 4.

L Nersisyan, R Samsonyan, A Arakelyan. CyKEGGParser: tailoring KEGG pathways to fit into systems biology analysis workflows. F1000Research. 2014. Version 2. 3: 145.

Funding

Modeling the effects of cigarette and e-cigarette smoke on oral and gut microbiome

Faculty research grant from EIF and PMI Science

PI: Lilit Nersisyan

Year: 2022

Open Positions

Open positions up to internships. For more information email the lab supervisor Dr. Lilit Nersisyan.